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Martin-Luther-Universität Halle-Wittenberg | |||
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Becker R, Wolff I (2000)
Die Umweltrelevanz des Chemieunfalls in Schönebeck und mögliche gesundheitliche Auswirkungen auf den Menschen.
Forschungsbericht 76213/23/97/H, ISBN 3-86010-589-2 (CIP-Einheitsaufnahme)
Kooperationspartner:
Ministerium für Arbeit, Frauen, Gesundheit und Soziales des Landes Sachsen-Anhalt
Gesundheitsamt Landkreis Schönebeck
Landesamt für Umweltschutz Sachsen-Anhalt
Ministerium für Raumordnung und Umwelt des Landes Sachsen-Anhalt
Otto-von-Guericke Universität Magdeburg; Monitoring Zentrum zur Erfassung der Häufigkeiten von Fehlbildungen und Anomalien
Raub JA, Carratu MR, Chen Q, Cotti G, Hazucha MJ, Jantunen M, Lahmann E, Lauriola P, Natieu-Nolf M, Pankow D, Penney DG, Sokal JA, Sullivan FM (1999)
Carbon monoxide.
Environmental Health Criteria 213, World Health Organization Geneva, 1-464
Foth H (1999)
Ecotoxicology.
In: Toxicology. Ed.: Marquardt H, Schäfer S, McClellan R, Welsch F. Academic Press (San Diego, London, Boston, New York, Sydney, Tokyo, Toronto) 1067-1085
Pankow D (2000)
History of carbon monoxide toxicology.
In: DG Penney (ed.) Carbon monoxide toxicity.
CRC Press Boca Raton (USA), 1-17
Schrader E, Klaunick G, Jorritsma U, Neurath H, Hirsch-Ernst KI, Kahl GF, Foth H (1999)
High-performance liquid chromatographic method for símultaneous determination of [ 1-methyl-14 C] caffeine and its eight major metabolites in rat urine.
J of Chromatography B 726: 195-201
Foth H (1999)
Speichelsekretion und Arzneimittel beim alten Menschen.
Zahnärztliche Mitteilungen 22: 50-56
Runge DM, Runge D, Foth H, Strom SC, Michalopoulos GK (1999)
STAT 1a /1b STAT 3 and STAT 5: expression and association with c-MET and EGF-receptor in long-term cultures of human hepatocytes.
Biochem and Biophy Res Commun 265: 376-381
Hüttner E, Götze A, Nikolova T (1999)
Chromosomal aberrations in humans as genetic endpoints to assess the impact of pollution.
Mutation Research 445: 251-257
Pankow D, Damme B (1999)
Carbon Monoxide Generation from Trihalomethane Metabolism in Rats. Indoor Built Environ 8: 203-208
Runge DM, Runge D, Dorko K, Pisarov LA, Lecke K, Kostrubsky VE, Thomas D, Strom SC, Michalopoulos GK (1999)
Epidermal growth factor- and hepatocyte growth Factor-receptor activity in serum-free cultures of human hepatocytes.
Journal of Hepatology 30; 265-274
Runge DM, Bowen WC, Katyal S, Runge D, Suski V, Michalopoulos GK (1999)
Expression of the Human Hepatocyte Growth Factor cDNA in Primary Cultures of Rat Hepatocytes.
Biochemical and Biophysical Research Communications 257: 199-205
Runge D, Runge DM, Daskalakis N, Lubecki KA, Bowen WC, Michalopoulos GK (1999)
Matrix-Mediated Changes in the Expression of HNF-4a Isoforms and in DNA-Binding Activity of ARP-1 in Primary Cultures of Rat Hepatocytes.
Biochemical and Biophysical Research Communications 259: 651-655
Runge DM, Runge D, Foth H, Strom SC, Michalopoulos GK (1999)
STAT 1a /1b , STAT 3 and STAT 5: Expression and association with c-MET and EGF-receptor in long-term cultures of human hepatocytes.
Biochem and Biophys Res Commun 265: 376-381
Schrader E, Hirsch-Ernst KI, Scholz E, Kahl GF, Foth H (2000)
Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in primary cultured rat alveolar type II cells.
Drug Metabolism and Disposition 28, 2: 180-185
Jorritsma U, Schrader E, Klaunick G, Kapitulnik J, Hirsch-Ernst KI, Kahl GF, Foth H (2000)
Monitoring of cytochrome P-450 1A activity by determination of the urinary pattern of caffeine metabolites in Wistar and hyperbilirubinemic Gunn rats.
Toxicology 144: 229-236
Runge D, Fleig WE, Michalopoulos GK, Strom SC, Runge DM (2000)
Hepatozytentransplantation.
DMW Deutsche Medizische Wochenschrift 125, 397-400
Runge D, Köhler C, Kostrubsky VE, Jäger D, Lehmann T, Runge DM, May U, Beer Stolz D, Strom SC, Fleig WE, Michalopoulos GK (2000)
Induction of Cytochrome P450 (CYP) 1A1, CYP1A2, and CYP3A4 but Not of CYP2C9, CYP2C19, Multidrug Resistance Associated Protein (MRP-1) by Prototypical Inducers in Human Hepatocytes.
Biochemical and Biophysical Research Communications 273, 333-341
Becker R, Hüttner E, Nikolova T, Wolff I, Foth H (1999)
Cytogenetic monitoring of a human population after an accidental vinyl chloride exposure.
Schriftenreihe der Deutschen Geologischen Gesellschaft 9, S. 12, Umwelt 2000 - Geowissenschaften für die Gesellschaft, 22.-25.09. Halle/S.
Runge D, Runge DM, Lubecki KA, Thomas D, Michalopoulos GK (1999)
Re-differentiation of rat hepatocytes in culture: Effects of EHS-gel on HNF4, ARPI, EAR3, PPAR and RXR.
FASEB J. 13 (4), A348, EB Meeting 16.-21.04., Washington DC
Runge D, Runge DM, Kostrubsky VE, Beer-Stolz D, Lubecki KA, Dorko K, Esplen JE, Thomas D, Strom SC, Watkins S, Michalopoulos GK (1999)
Maintenance of liver specific functions in long term cultures of human hepatocytes.
FASEB J. 13 (4), A347, EB Meeting 16.-21.04., Washington DC
Runge DM, Runge D, Thomas D, Lubecki KA, Dorko K, Esplen JE, Strom SC, Michalopoulos GK (1999)
Association of MET with STAT-1, STAT-3, and STAT-5 in cultures of human hepatocytes.
FASEB J. 13 (5), A684, EB Meeting 16.-21.04., Washington DC
Runge D, Runge DM, Kostrubsky VE, Beer-Stolz D, Dorko K, Esplen JE, Thomas D, Strom SC, Watkins S, Michalopoulos GK (1999)
Aufrechterhaltung leberspezifischer Funktionen in serumfreien Langzeit-Kulturen humaner Hepatozyten.
Z. Gastroenerology 37, 71, 15. Jahrestagung der GASL, 29.-30.01., Kiel
Runge DM, Runge D, Dorko K, Pisatov LA, Leckel K, Kostrubsky VE, Thomas D, Strom SC, Michalopoulos GK (1999)
Association of MET with STAT-1, STAT-3, and STAT-5 in cultures of human hepatocytes.
Z. Gastroenterology 37, 71, 15. Jahrestagung der GASL, 29.-30.01., Kiel
Runge D, Kostrubsky VE, Runge DM, Beer-Stolz D, Karathanasis S, Kietzmann T, Lubecki KA, Strom SC, Watkins S, Jungermann K, Michalopoulos GK (1999)
Serum-free long-term cultures of human hepatocytes: Maintenance of liver enriched transcription factors and liver specific functions.
Abstraktband 8th Biennial International Congress on: Liver Development, Gene Regulation and Disease, S. 95, 02.-05.06. Orvieto (Italien)
Runge D, Runge DM, Michalopoulos GK, Fleig WE (1999)
EHS-gel mediated changes in the expression of HNF-4 and ARP-1 transcription factors in rat hepatocyte cultures.
Falk Symposium No 113: 16, 16.-18.09. Regensburg
Runge DM, Runge D, Michalopoulos GK, Foth H (1999)
STAT activation mediated by HGF and EGF through their receptors in primary cultures of human hepatocytes.
Falk Symposium No 113: 17, 16.-18.09. Regensburg
Runge D, Kostrubsky VE, Runge DM, Beer-Stolz D, Strom SC, Michalopoulos GK (1999)
Maintenance of human hepatocytes in long-term serum-free cultures.
7th European ISSX Meeting Vol 14, 187, 22.-26.08. Budapest
Wolff I, Müller, P, Stock TW, Bauer S, Foth H (1999)
Generation of DNA single-strand breaks by complex mixtures.
Naunyn-Schmiedeberg´s Arch Pharmacol 359, Suppl, R 666
Achim CL, Dorsey RW, Bruner MK, Stauffer WR, White MG, Runge DM, Petersen BE, Michalopoulos GK (1999)
In vitro and in vivo neurotrophic effects of human hepatocyte growth factor.
1999 Annual Meeting, Miami Beach, Florida (USA)
Stock TW, Müller P, Wolff I, Bahn H, Foth H (1999)
Normal Human Bronchial epithelial cells as a tool to monitor gentoxic effects of complex mixtures.
Naunyn-Schmiedeberg´s Arch Pharmacol 359, Suppl, R 693
Wolff I, Müller P, Stock TW, Bauer S, Foth H (1999)
Genotoxic activity of complex mixtures in solid waste from plasma etching in lymphocytes, bronchial cells and hepatocytes.
Toxicology Letters, Vol 109, Suppl 1, 47
Wolff I, Bauer S, Müller P, Stock TW, Pelzing M, Foth H (1999)
Toxicological characterization of complex mixtures from plasma etching processes.
Schriftenreihe der Deutschen Geologischen Gesellschaft 9, S. 155, Umwelt 2000 - Geowissenschaften für die Gesellschaft, 22.-25. 09., Halle/S.
Runge DM, Runge D, Foth H, Strom SC, Michalopoulos GK (2000)
EGF-Rezeptor und MET: Cross-talk der Rezeptoren vermittelt durch STAT-Proteine.
Z Gastroenterologie 38: 95
Köhler C, Runge DM, Foth H, Fleig WE, Strom SC, Michalopoulos GK, Runge D (2000)
P-Glykoprotein und MRP (Multidrug Resistance-associated Protein) Expression in serumfreien Langzeitkulturen humaner Hepatozyten.
Z Gastroenterologie 38: 104
Wolff I, Becker R, Hüttner E, Nikolova T, Foth H (2000)
Cytogenetic monitoring of a human population after an accidental vinyl chloride exposure.
Naunyn-Schmiedeberg´s Arch Pharmacol 361, Suppl., R 176
Köhler C, Weidauer E, Runge DM, Lehmann T, Röhrdanz E, Tran Thi QH, Kahl R, Foth H (2000)
Oxidative stress alters expression of P-glycoprotein and multidrug resistance-associated protein, but not antioxidant enzymes in lung tumor cell lines.
Naunyn-Schmiedeberg´s Arch Pharmacol 361, Suppl, R 163
Runge DM, Stock TW, Beer Stolz D, Taege C, Runge D, Hofmann S, Silber R-E, Holzhausen H-J, Foth H (2000)
Acute phase response and activation of hepatocyte growth factor receptor after ethanol and dichlormethane treatment of normal human bronchial epithelial cells in culture. Naunyn-Schmiedeberg´s Arch Pharmacol 361, Suppl, R 161
Lehmann T, Weidauer E, Röhrdanz E, Tran Thi QH, Kahl R, Foth H (2000)
Influence of paraquat and hydrogen peroxide to antioxidant enzymes (cat, MNSOD) and mdr1b in rat alveolar type II pneumocytes.
Naunyn-Schmiedeberg´s Arch Pharmacol 361, Suppl, R 142
Runge D, Runge DM, Jäger D, Kostrubsky VE, Strom SC, Michalopoulos GK, Fleig WE (2000)
Cytochrome P450 gene expression and enzymatic activity in long-term serum-free human hepatocyte cultures.
Naunyn-Schmiedeberg´s Arch Pharmacol 361, Suppl, R166
Runge D, Runge DM, Jäger D, Strom S, Fleig WE, Michalopoulos GK (2000)
Use of human hepatocyte cultures as a model for evaluation of enzymes involved in immunosuppression and inflammatory processes.
Falk Workshop 27.-28.01., Köln
Köhler C, Runge DM, Foth H, May U, Fleig WE, Strom SC, Michaolopoulos GK, Runge D (2000)
Regulation of P-Glycoprotein and MRP (multidrug resistance-associated protein) by cytochrome P450 inducers in serum-free cultures of human hepatocytes.
Falk Workshop 27.-28.01., Köln
Runge D, Runge DM, Köhler C, Lehmann T, Jäger D, May U, Foth H, Dorko H, Strom SC, Michalopoulos GK, Fleig WE (2000)
Expression of membrane transporter and cytochrome P450 proteins in serum-free long-term human hepatocyte cultures.
FASEB J 4, Vol 14, A183, Experimental Biology Meeting, San Diego, 15.-18.04.
Runge DM, Runge D, Foth H, Strom SC, Michaolopoulos GK (2000)
EGF-receptor and Met: crosstalk between the two growth factor receptors mediated by STAT proteins in human hepatocytes.
FASEB J 4, Vol 14, A722, Experimental Biology Meeting, San Diego, 15.-18.04.
Runge DM, Runge D, Foth H, Strom SC, Michaolopoulos GK (2000)
Activation of STAT proteins by HGF and EGF in human hepatocytes.
J of Hepatology, Suppl. 2, Vol 32, EASL Meeting 29.04.-03.05., Rotterdam/Niederlande
Runge D, Runge DM, Jäger D, Kostrubsky VE, Strom SC, Michalopoulos GK, Fleig WE (2000)
Expression and enzymatic activities of cytochrome P450 species in human hepatocytes.
J of Hepatology, Suppl. 2, Vol 32, EASL Meeting 29.04.-03.05. Rotterdam/Niederlande
Runge DM, Runge D, Foth H, Strom SC, Michalopoulos GK (2000)
EGF-receptor and MET: Cross-talk between the two growth factor receptors mediated by STAT-proteins in human hepatocytes.
Falk Workshop 27.-28.01., Köln
Neumann T, Heinrich H, Schuhmann H, Heublein DH, Burnett HC, Müller SP, Schulz R, Heusch G, Holtz J (2000)
Long-term ANP evaluation in rats: No induction of myocardial apoptosis via the ANP-cGMP axis.
Pflug Arch Eur J Phy 439 (6): R 394
Müller SP, Krivokuca M, Pregla R, Darmer D, Holtz J (2000)
Myokard-Apoptose in senilen Ratten durch chronische Hemmung der NO-Synthase: verminderte Hochdruckentwicklung, aber erhöhte Anfälligkeit für Myokardversagen.
Z Kardiol 89 (Suppl 5) 707
Neumann T, Heinrich H, Schuhmann H, Heublein DH, Burnett HC, Müller SP, Schulz R, Heusch G, Holtz J (2000)
Long-term ANP evaluation in rats: No induction of myocardial apoptosis via the ANP-cGMP axis.
Eur J Heart Failure (Suppl. 2) 44
Müller SP, Krivokuca M, Werdan K, Darmer D, Foth H, Holtz J (2000)
Age-specific right ventricular decompensation in response to pulmonary hypertension in senescent rats.
Toxicology Letters 116 (Suppl. 1), 78 (285)
Lehmann T, Köhler Ch, Runge DM, Foth H (2000)
Expression of multidrug resistance proteins and CYP2E1 in serum-free cultured human bronchial epithelial cells.
Toxicology Letters 116 (Suppl. 1), 47 (175)
Müller P, Wolff I, Bauer S, Stock TW, Foth H (2000)
Assessment of DNA damage induced by complex mixtures of halogenated hydrocarbons using the alkaline comet assay.
Toxicology Letters 116 (Suppl. 1), 36 (136)
Köhler Ch, Lehmann T, Kostrubsky VE, Stolz DB, Strom SC, Michalopoulos GK, Runge DM, Runge D (2000)
Different induction pattern of Cytochrome P450 and multidrug resistance proteins expression in serum-free human hepatocyte cultures.
Toxicology Letters 116 (Suppl. 1), 104 (382)
Runge DM, Runge D, Hofmann S, Decker C, Silber RE, Foth H (2000)
Activation of acute phase response by Ethanol but not Dichloromethane in primary cultures of human bronchial epithelial cells.
Toxicology Letters 116 (Suppl. 1), 46 (170)
Müller SP, Krivokuca M, Rohrbach S, Darmer D, Foth H, Holtz J (2000)
Age-specific decompensation under chronic NO-synthase expression in rats is prevented by application of Insulin-like growth-factor-I.
Circulation 102 (Suppl. 2): II-134
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