Martin-Luther-Universität Halle-Wittenberg
Forschungsbericht Berichtszeitraum:01.01.99 - 31.12.00

Medizinische Fakultät

Institut für Pharmakologie und Toxikologie

Sektion Pharmakokinetik

Veröffentlichungen


Herausgeberschaften 1999 :   0
Herausgeberschaften 2000 :   0
 
Monographien 1999 :   0
Monographien 2000 :   0
 
Buchbeiträge 1999 :   1
Buchbeiträge 2000 :   1
 
Artikel in Zeitschriften 1999 :   12
Artikel in Zeitschriften 2000 :   8
 
Artikel in Konferenzbänden 1999 :   1
Artikel in Konferenzbänden 2000 :   0
 

Buchbeiträge 1999

M. Weiss (1999)
Pharmacokinetic Rationale for Arterial Drug Infusion.
In: Intra-arterial Chemotherapy in Head and Neck Cancer. (A. Echardt, ed.), Reinbeck: Einhorn-Presse Verlag, pp. 38-44
 

Buchbeiträge 2000

M. Weiss (2000)
Physiological Modelling and the Effect Site.
In: On the Study and Practice of Intravenous Anaesthesia.(J. Vuyk, F. Engbers, S. Groen-Mulder, eds.), Dordrecht; Boston; London: Kluver Academic Publishers, pp. 3-16

Artikel in Zeitschriften 1999

Schalla, M. and Weiss. M. (1999)
Pharmacokinetic curve fitting using numerical inverse Laplace transformation.
Eur. J. Pharm. Sci. 7: 305-309

Lötsch, J., Weiss, M., Ahne, G., Kobal, G., and Geisslinger, G. (1999)
Pharmacokinetic modeling of M6G formation after oral administration of morphine in healthy volunteers.
Anesthesiology 90: 1026-1038

Kuhlmann, O., Hofmann, S., and Weiss, M. (1999)
Determination of idarubicin and idarubicinol in rat plasma using reversed-phase HPLC and fluorescent detection.
J. Chrom. B 728: 279-282

Sanchez-Navarro, A., Casquero-Dorado, A.C., and Weiss, M. (1999)
Distribution and binding kinetics of ciprofloxacin and ofloxacin in the hindlimb of the rat.
Pharmaceut. Res. 16: 587-591

Lánsky, P. and Weiss, M. (1999)
Does the dose-solubilitiy ratio affect the mean dissolution time of drugs?
Pharmaceut. Res. 16: 1472-1478

Weiss, M. (1999)
Cellular pharmacokinetics: Effects of cytoplasmic diffusion and binding on organ transit time distribution.
J. Pharmacokin. Biopharm. 27: 233-255

Weiss, M. (1999)
The anomalous pharmacokinetics of amiodarone explained by nonexponential tissue trapping.
J. Pharmacokin. Biopharm. 27: 383-396

Kuhlmann, O., Roberts, M.S., and Weiss, M. (1999)
Disposition of p-aminohippuric acid (PAH) and kinetics of the metabolite p-acetylaminohippuric acid (PAAH) in the in-situ perfused rat liver.
Naunyn-Schmiedeberg's Arch. Pharmacol. 359: R120

Weiss, M. (1999)
Modeling the anomalous pharmacokinetics of amiodarone.
Clin. Pharmacol. Ther. 65: 180

Weiss, M., Keiding, S., Schiott, K., Munk, O., and Roelsgaard, K. (1999)
Recirculatory pharmacokinetic models of PET radiotracers: Application to 13N-Ammonia.
Eur. J. Clin. Invest. 29: 92, p.29

Weiss, M., Sziegoleit, W., and Hübner, G.I. (1999)
Effects of hemodynamics on the pharmacokinetics of sorbitol in healthy volunteers: Recirculatory vs. compartmental modeling.
Eur. J. Pharm. Sci. 8: A149

Bariszlovich, A., Struck, H.-G., Weiss, M., and Kuhlmann, O. (1999)
Zum Verlauf des Kammerwasser- und Plasmaspiegels von Diclofenac bei intravenöser Applikation vor der Kataraktoperation.
Klin. Monatsbl. Augenheilkd. 215: 1
 

Artikel in Zeitschriften 2000

Foster, K.A., Mellick, D.G., Weiss, M., and Roberts, M.S. (2000)
An isolated in-situ rat head perfusion model for pharmacokinetic studies.
Pharmaceut. Res. 17: 127-134

Ring, A., Tothfalusi, L., Endrenyi, L., and Weiss, M. (2000)
Sensitivity of empirical metrics of rate of absorption in bioequivalence studies.
Pharmaceut. Res. 17: 583-588

Weiss, M., Kuhlmann, O., Hung, D., and Roberts, M.S. (2000)
Cytoplasmic binding and disposition kinetics of diclofenac in the isolated perfused rat liver.
Brit. J. Pharmacol. 130: 1331-1338

Roberts, M.S., Wu, Z., and Weiss, M. (2000)
Kinetics of propranolol uptake in muscle, skin, and fat of the isolated perfused rat hindlimb.
Eur. J. Pharm. Sci. 11: 165-172

Roberts, M.S., Anissimov, Y.G., and Weiss, M. (2000)
Using the convection-dispersion model and transit time density functions in the analysis of organ distribution kinetics.
J. Pharm. Sci. 89: 1579-1586

Kuhlmann, O., Jeschke, O., and Weiss, M. (2000)
Effect of bile acid on membrane permeation and absorption kinetics of diclofenac.
Naunyn Schmiedeberg's Arch. Pharmacol.361: R122

Struck, H.-G., Bariszlovich, A., Kuhlmann, O., and Weiss, M. (2000)
Diclofenac level in aqueous humor and in plasma after i.v.-injection.
Ophthalmic Res. Sept. 2000, 140: 3333

Kang, W., Kuhlmann, O., and Weiss, M. (2000)
Effect of rutin on pharmacokinetics and pharmacodynamics of idarubicin in the isolated perfused rat heart.
Eur. J. Pharm. Sci. 11: S92, PO-188


Artikel in Konferenzbänden 1999

Struck, H.-G., Stoldt, G., Kuhlmann, O., and Weiss, M. (1999)
Zum Verlauf der Diclofenac-Konzentration im Kammerwasser nach präoperativer Gabe bei der Kataraktextraktion.
In: G. Duncker et al. (Hrsg.), 12. Kongress der DGH 1998, Springer-Verlag Berlin Heidelberg, S. 82-87

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