Martin-Luther-Universität Halle-Wittenberg
Forschungsbericht Berichtszeitraum:01.01.99 - 31.12.00

Medizinische Fakultät

Institut für Medizinische Immunologie

Veröffentlichungen


Herausgeberschaften 1999 :

 

0

Herausgeberschaften 2000 :

 

1

 

 

 

Monographien 1999 :

 

0

Monographien 2000 :

 

0

 

 

 

Buchbeiträge 1999 :

 

0

Buchbeiträge 2000 :

 

5

 

 

 

Artikel in Zeitschriften 1999 :

 

15

Artikel in Zeitschriften 2000 :

 

25

 

 

 

Artikel in Konferenzbänden 1999 :

 

0

Artikel in Konferenzbänden 2000 :

 

0

 

 

 


 

Herausgeberschaften 2000

Buchherausgabe: Langner, J., and S. Ansorge (eds):

Cellular Peptidases in Immune Functions and Diseases 2, Kluwer Academic/Plenum Publishers, New York, Boston etc. 2000. ISBN: 0-306-46383-0 (= Adv. Exp. Med. Biol. Vol. 477)

 


 

 

Buchbeiträge 2000

Kehlen, A., Langner, J., Riemann, D.:

Transforming growth-factor-b increases the expression of aminopeptidase N/CD13 mRNA and protein in monocytes and monocytic cell lines.

Adv. Exp. Med. Biol. 477 (2000) 49-56

 

Riemann, D., Roentsch, J., Hause, B., Langner, J., Kehlen, A.:

Cell-cell contact between lymphocytes and fibroblast-like synoviocytes induces lymphocytic expression of aminopeptidase N/CD13 and results in lymphocytic activation.

Adv. Exp. Med. Biol. 477 (2000) 57-66

 

Navarrete Santos, A., Langner, J., Riemann, D.:

Enzymatic activity is not a precondition for the intracellular calcium increase mediated by mAbs specific for aminopeptidase N/CD13.

Adv. Exp. Med. Biol. 477 (2000) 43-47

 

Lendeckel, U., Kähne, T., Riemann, D., Neubert, K., Arndt, M., Reinhold, D.:

Review: The role of membrane peptidases in immune functions.

Adv. Exp. Med. Biol. 477 (2000) 1-24

 

Bank, U., Krüger S ., Langner, J., Roessner, A.:

Review: Peptidases and peptidase inhibitors in the pathogenesis of diseases.

Adv. Exp. Med. Biol. 477 (2000) 349-378

 


Artikel in Zeitschriften 1999

Riemann, D., Kehlen, A., Langner, J.:

CD13 - not just a marker in leukemia typing.

Immunol. Today 20 (1999), 83-88

 

Kehlen, A., Thiele, K., Riemann, D., Rainov, N., Langner, J.:

Interleukin-17 stimulates the expression of IkB-a mRNA and the secretion of IL-6 and IL-8 in glioblastoma cell lines.

J. Neuroimmunol. 101 (1999) 1-6

 

Reichert S., Riemann, D., Plaschka, B., Machulla, H.K.:

Early-onset periodontitis in patients with Ehlers-Danlos syndrome type III.

Quintessence Int. 30 (1999) 785-790

 

Markwardt, F., Klapperstück, M., Löhn, M., Riemann, D., Büttner, C., Schmalzing, G.:

Purinreceptors in human B-lymphocytes.

Prog. Brain Res. 120 (1999) 345-353

 

Biewald, J., Brömme, H.-J., Nilius, R., Langner, J.: Effects of twelve months ethanol feeding on rat liver metabolic activity.

Intern. J. Mol. Med. 3 (1999) 279-284

 

Langner, J., Thiem, M., Böhning V.: Comparative determination of the antiproteolytic potential of therapeutically used protein preparations.

Intern. J. Mol. Med. 4 (1999) 605-610

 

Lang H., Machulla H., Müller C.-H., Müller C., Ottinger H., Schröder S., Schulze-Rath R., Winterhager J., Goldmann S. (Kommission für Knochenmarktransplantation)

Empfehlungen der Deutschen Gesellschaft für Immungenetik (DGI) für die Spenden von Knochenmark- und peripheren hämatopoetischer Stammzellen freiwilliger nicht verwandter Spender.

DGI Aktuell (1999) 1-14, Sonderausgabe

 

Dorak M.T., Lawson T., Machulla H.K.G., Mills K.I., Darke., Burnett A.K.

Contribution of the HLA-DRB4 locus to childhood leukemia susceptibility is male-specific.

Blood 94 (1999) 1-8

 

Abstracts

 

Kehlen, A., Thiele, K., Navarrete Santos, A., Langner, J., Riemann, D. Cell-cell contact of lymphocytes increases mRNA expression of aminopeptidase N/CD13, IL-8, IkBa and phosphorylation of ERK1/2, Akt and CREB.

Eur. J. Cell Biol. 78(Suppl.49) (1999) 38

 

Neuhaus, K., Müller-Werdan, U., Riemann, D., Lautenschläger, C., Ziegler-Heitbrock, H.W.L., Zerkowski, H.R., Langner J., Werdan, K. Impact of cardiopulmonary-bypass assisted surgery on markers of monocyte

function.

Crit Care 3 (Suppl 1) (1999) P112.

 

Machulla H.K.G., Stepanowa A., Langner J., Taube K.-M.

HLA-A, B, C, DRB1, 3/4/5, DQB1 in psoriasis patients sharing atopic dermatitis.

Human Immunol. 60, Suppl.1 (1999) p.53

 

Müller L., Schaaf A., Kujat G., Kunze G., Langner J., Machulla H.K.G.

Gender and HLA in German patients with chronic lymphocytic leukemia.

Human Immunol. 60, Suppl.1 (1999) p.62

 

Machulla H.K.G., Müller L., Schaaf A., Kujat G., Kunze G., Langner J.

HLA type and onset age in patients with chronic lymphocytic leukemia.

Human Immunol. 60, Suppl.1 (1999) p.63

 

Machulla H.K.G., Schaaf A., Steinborn F., Krüger J., Rainov N.G.

HLA-A, B, C, DRB1, DRB3/4/5, DQB1 in glioma patients.

Human Immunol. 60, Suppl.2 (1999) p.83

 

Dorak M.T., Machulla H.K.G., Darke C., Poynton C.H., Barrett-Lee P., Burnett A.K.

The overall homozygosity rate for HLA class II supertypes is increased in malignancies.

Abstracts 25th Annual ASHI Meeting (New Orleans/USA, October 20-24, 1999) #5.2

Human Immunol. 60, Suppl.2 (1999) p.13

 

Artikel in Zeitschriften 2000

Ansorge, S., Langner, J., Bühling, F., Lendeckel, U.: Proteolytic signals from Magdeburg

Immunol. Today 21 (2000) 166-167

 

Kehlen, A., Olsen, J., Langner, J., Riemann, D.:

Increased lymphocytic aminopeptidase N/CD13 promoter activity after cell-cell contact.

J. Cell. Biochem. 80 (2000) 115-123

 

Thiele, K., Riemann, D., Navarrete Santos, A., Langner, J., Kehlen, A.:

Cell-cell contact of human T cells with fibroblasts changes lymphocytic mRNA expression: Increased mRNA expression of interleukin-17 and interleukin-17 receptor.

Eur. Cytokine Netw.11 (2000) 53-58

 

Navarrete Santos, A, Langner, J., Herrmann, M., Riemann, D.:

Aminopeptidase N/CD13 is directly linked to signal transduction pathways in monocytes.

Cell. Immunol. 200 (2000) 22-32

 

Navarrete Santos, A., Roentsch, J., Danielsen, E. M., Langner, J., Riemann, D.:

Aminopeptidase N/CD13 is associated with raft membrane microdomains in monocytes.

Biochem. Biophys. Res. Comm. 269 (2000) 143-148

 

Taubert, H., Thamm, B., Meye, A., Bartel, F., Rost, A.-K., Heidenreich, D., John, V., Brandt, J., Bache, M., Würl, P., Schmidt, H., Riemann, D.:

The p53 status in juvenile chronic arthritis and rheumatoid arthritis.

Clin. Exp. Immunol. 122 (2000) 264-269

 

Rainov, N.G., Krann, C.M., Banning, U., Riemann, D., Holzhausen, H.-J., Heidecke, V., Burger, K.J., Burkert, W., Körholz, D.:

Immune response induced by retrovirus-mediated HSV-tk/GCV pharmacogene therapy in patients with glioblastoma multiforme.

Gene Therapy 7 (2000) 1853-1858

 

Reichert S., Stein J., Gautsch A., Kloß C., Krüger J., Schaaf A., Langner J., Machulla H.K.G.

HLA-A, B, Cw, DQ-Merkmale in einer Gruppe deutscher Patienten mit rapid progressiver Parodontitis (RPP).

Dtsch Zahnärztl Z55 (2000) 502-507

 

Machulla H.K.G., Schaaf A.

Is there any necessity to replace the CDC screening technique by ELISA?

In:

Visuals of the 1st European Clinical Histocompatibility Workshop (Stresa Invitational 2000, ed. Terasaki P. I.), p. 51-52

 

Machulla H.K.G., Schönermarck U., Schaaf A., Müller L.P., Kloß C., Krüger J., Kunze G., Schönermarck G., Langner J.

HLA-A,B,Cw and DRB1, DRB3/4/5, DQB1, DPB1 frequencies in German IgA deficient individuals.

Scand. J. Immunol. 52 (2000) 207-211

 

Machulla H.K.G., Müller L.P., Schaaf A., Kujat G., Schönermarck U., Langner J.

Association of chronic lymphocytic leukaemia with specific alleles of the HLA-DR4:DR53:DQ8 haplotype in German patients

Int. J. Cancer (2000) (accepted 2000-11-02. # 3089R)

 

Abstracts

 

Kehlen, A., Lauterbach, R., Kabisch, U., Navarrete Santos, A., Riemann, D., Langner, J. Downregulation by the cytokines IL-1 and IL-4 of autotaxin expression fibroblast-like synoviocytes of patients with rheumatoid arthritis.

Eur. J. Cell. Biol. 79 (S50) (2000) 28.

 

Thiele, K., Wiese, C., Riemann D., Rainov, N., Langner, J Kehlen, A. Interleukin-17 effects and interleukin-17 receptor expression in glioblastoma cell lines.

Eur. J. Cell. Biol. 79 (S50) (2000) 69

 

Navarrete Santos, A, Langner, J., Riemann, D. Localization of aminopeptidase N/CD13 in the triton-insoluble fraction of monocytes.

Eur. J. Cell. Biol. 79 (S50) (2000) 59.

 

Meye, A., Taubert, H., Hinze, R., Bilkenroth, U., Göhring, B., Riemann, D., Heynemann, H.:

Somatic VHL but not p53 mutations in sporadic clear cell renal cell carcinoma.

Eur. Urol. 37 (Suppl.2) (2000) 130

 

Kehlen, A., Thiele, K., Riemann D., Langner, J. Expression and signaling of interleukin-17 receptor in fibroblast-like synoviocytes of patients with rheumatoid arthritis.

Immunobiology. 203 (1-3) (2000) 140.

 

Machulla H.K.G., Schaaf A., Krüger J., Langner J., Hillig F., Schabel J., Heynemann H.

HLA-A, B, C, DRB1/3/4/5, DQB1 in Renal Cell Carcinoma.

Human Immunol. 61 Suppl.1 (2000) p.78

 

Batnasan D., Steinborn F., Schaaf A., Krüger J., Machulla H.K.G.,

HLA frequencies of Khalha Mongolians.

Human Immunol. 61 Suppl.1 (2000) p.125

 

Reichert S., Stein J., Gautsch A., Machulla H.K.G.

HLA in German patients with rapidly progressive periodontitis (RPP) in comparison to resistant controls.

J. Clin. Periodontol. 27, Suppl.1 (2000) p.81

 

Dorak M.T., Sproul A., Machulla H.K.G., Burnett A.K., Ginson B.

Confirmation of the male-specific HLA-DRB4*01 association in childhood leukemia.

Eur. J. Immunogenet. 27 (2000) p.262

 

Dorak M.T., Lawson T., Machulla H.K.G., Burnett A.K.

Evidence for heterozygote advantage and sexual antagonism in MHC-mediated prenatal selection.

Eur. J. Immunogenet. 27 (2000) p.257

 

Dorak M.T., Lawson T., Machulla H.K.G., Schaaf A., Darke C., Burnett A.K.

Prenatal heterozygote advantage concerns supertypical families of HLA-DRB haplotypes and is male-specific.

Human Immunol. 61 (2000) p.55

 

Dorak M.T., Lawson T., Machulla H.K.G., Darke C., Burnett A.K.

The B1-allelic polymorphism of HSP70-2 correlates with the genealogy of HLA-DRB1 genes.

Human Immunol. 61 (2000) p.54

 

Müller L.P., Schaaf A., Kujat G., Langner J., Schmoll H.J., Machulla H.K.G.

HLA in patients with chronic lymphocytic leukemia (CLL) depending on gender and age at disease onset.

Onkologie 23, Sonderheft 7 (2000) 44

 

Matthews V.B., Witt C., Cheong K., Hollongsworth P.N., Machulla H.K.G., French M., Teranteroi D., Price P.

Regulation of IgA levels by MHC genes: Implications in IgA Deficiency and IgA Nephropathy.

Abstracts of 24th Ann. Meeting of the Australasian and South East Asian Tissue Typing Association.

(30. Nov.-3. Dec. 2000, Perth, Western Australia)

 

Dorak M.T., Machulla H.K.G., Darke C., Poynton C.H., Barrett-Lee P., Burnett A.K.

The overall homozygosity rate for HLA class II supertypes is increased in malignancies.

Abstracts 25th Annual ASHI Meeting (New Orleans/USA, October 20-24, 1999) #5.2

Human Immunol. 60, Suppl.2 (1999) p.13

 


 

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